To use Rick Simpson Oil (RSO), start with a small dose and slowly increase it as your body gets used to the effects.
RSO comes in many forms, including oral syringes, tinctures, capsules, gummies, suppositories, and topical applications.
Each method works differently in terms of onset and intensity, so the best choice depends on your goals and comfort level.
This guide walks you through how to use RSO safely and effectively, whether you’re new or fine-tuning your routine.
What is RSO?
Rick Simpson Oil (RSO) is a full-spectrum cannabis extract known for its high THC content and powerful effects. It was originally created by Rick Simpson, a Canadian medical cannabis advocate who used it to treat his own skin cancer and later shared his method publicly.
What sets RSO apart is that it keeps all the natural compounds found in cannabis, like cannabinoids, terpenes, and flavonoids, so you get the full therapeutic potential of the plant.
Because it’s so potent, RSO is mostly used for medical reasons, especially to help with cancer, chronic pain, and other serious health conditions.
How to Use RSO: 5 Basic Steps
RSO can be simple to work into your routine, especially when you know what to expect. Here’s how to get started.
1. Consult With a Healthcare Professional
Before you start using RSO, talk to a healthcare provider, especially if you’re taking medications or managing a health condition.
RSO contains high levels of THC and can interact with other treatments. A provider familiar with cannabis can help you figure out if it’s a good fit and guide you on how to start.
Since there are no official dosing guidelines, it helps to have someone in your corner who can track your progress and make adjustments as needed.
2. Determine Your Delivery Method
RSO comes in a few different formats, and each one works a little differently.
Oral syringes are the most versatile. You can take the oil under your tongue, swallow it, mix it with food, or even use it on your skin.
Tinctures are great for faster effects and easier measuring. Just drop some under your tongue and you’re good to go.
Capsules offer a mess-free, discreet option with consistent doses. Gummies add flavor and convenience, though they can be slightly less potent.
Suppositories are another option if you want full-body effects without the head high.
Note that you cannot smoke RSO, due to its composition.
Pick the method that fits your lifestyle and comfort level.
3. Determine Your Dosage
When it comes to dosing RSO, it’s best to start small and take your time. Rick Simpson recommends a daily dose of about one full grain of rice (~30 mg), split into three doses of one-third each.
But you don’t need to hit this amount right away. Ease into it slowly.
Pay attention to how your body responds. Things like your weight, metabolism, symptoms, and THC tolerance all play a role.
If you’re using capsules or gummies, check the label and adjust your intake to match the strength.
The goal is to find a dose that feels manageable and gives you the relief you’re looking for, without overdoing it.
4. Consume
You can take RSO in a few different ways – capsules, tinctures, gummies, or straight from the syringe.
Swallow it with food, or if you’re using a tincture, try holding it under your tongue for faster absorption.
Pick one method and stick with it. A consistent routine helps your body adjust and build tolerance more gradually.
RSO takes time to kick in, so avoid driving or anything that requires quick reactions until you know how it affects you.
Eating beforehand can also help prevent an upset stomach and help the effects feel more balanced.
5. Observe & Adjust Accordingly
Pay attention to how your body responds, especially in the first few days.
RSO usually kicks in within 45 to 90 minutes and can last 6 to 8 hours. Some people feel the effects sooner or later, depending on their metabolism and whether they’ve eaten.
Keep track of how you feel. Note changes in pain relief, sleepiness, dizziness, or anything else that stands out.
If you’re not feeling enough, or a little too much, adjust your dose slowly. Don’t double up right away. Give it a few days between changes.
Your goal is to find what works best for you, with minimal side effects.
How to Use Different Types of RSO Products
Each RSO product works a little differently. Here’s how to use each one and what to expect.
RSO Syringes
RSO syringes give you the most flexibility when it comes to dosing. You can take the oil under your tongue, swallow it directly, or mix it with food.
Start with a dose about one-third the size of a full grain of rice and increase slowly as needed. Syringes are great for control, but the oil can be sticky and strong-tasting, so go slow and measure carefully.
RSO Tinctures
RSO tinctures are made for sublingual use – just place a few drops under your tongue and hold them there for quicker absorption.
They’re easier to measure than syringes and often come in flavored or carrier oil-based options. If you want faster effects without the mess of thick oil, tinctures are a solid choice.
RSO Edibles
RSO edibles, like gummies or baked goods, come with pre-measured doses that are easy to take.
It can take 45 minutes to 2 hours to feel the effects, but they tend to last for several hours. Edibles are a good pick if you want long-lasting relief, better flavor, and no cleanup.
RSO Capsules
RSO capsules are a simple, mess-free way to take RSO. Just swallow one with water like a regular supplement.
You’ll usually start to feel the effects in 60 to 90 minutes. Capsules make daily use easy, but since the dose is fixed, you can’t adjust it the way you can with a syringe or tincture.
RSO Suppositories
RSO suppositories are used rectally or vaginally and are often chosen for full-body or localized relief – without the intense head high.
Effects can start within 15 to 30 minutes. Because this method bypasses digestion, the effects may feel more physical and less mentally intense than oral RSO.
Always follow the product instructions closely for safe use.
How Much RSO Should You Take?
Start with very small doses of RSO and gradually increase until you achieve your desired result.
Start by taking a small dose of RSO oil, about one-third of a rice grain-sized oil dollop (or an equivalent of 30mg if using a product other than pure RSO oil from an oral syringe).
Take this dose three times per day (so you get 30mg total) and slowly increase it until you get your desired results.
If you’re using RSO for cancer, see our RSO protocol. Otherwise, see our RSO dosage guide for more information.
How Long Does RSO Take to Work?
When you take RSO by mouth, the effects usually start within 45 to 90 minutes. That’s because the oil has to move through your digestive system before it enters your bloodstream.
Onset timing depends on your method and whether you’ve eaten.
If you take it on an empty stomach, you might feel it sooner. If you’ve eaten recently, it could take a little longer.
Holding RSO under your tongue (sublingual use) can work faster – around 30 minutes – but not everyone prefers this method because of the thick, sticky texture.
No matter how you take it, don’t rush your next dose. Wait at least 2 hours to see how it hits. The effects build slowly and can come on stronger than you expect.
How Long Do The Effects of RSO Last?
RSO tends to stick around. Most people feel the effects for 6 to 8 hours, sometimes even longer, depending on their dose, tolerance, and metabolism.
Because it’s a full-spectrum oil, your body absorbs it slowly, and it stays active longer than other cannabis products. For many, that means steady, full-body relief that lasts well into the day (or night).
This makes RSO a good fit if you’re dealing with things like chronic pain, sleep problems, or long-lasting stress. Just remember: once it kicks in, it stays with you. That’s why starting low is the safest move.
Can You Smoke RSO?
Nope – RSO isn’t made for smoking. It’s thick, sticky, and meant to be taken orally, used topically, or (in some cases) as a suppository.
Smoking it can expose you to leftover solvents if it wasn’t purged properly. Even high-quality RSO doesn’t burn clean – it clogs devices, burns unevenly, and just isn’t worth the hassle.
If you want something to smoke or vape, stick with flower or distillate cartridges. RSO is best for long-lasting, therapeutic use, not lighting up.
Conclusion: Getting the Most Out Of RSO
RSO is a powerful, full-spectrum cannabis extract that’s best used with a thoughtful, low-and-slow approach.
Start with a small dose, stick to a routine, and adjust as needed based on how your body responds.
Whether you’re using a syringe, tincture, edible, capsule, or suppository, the right method comes down to your comfort and goals.
RSO can take time to kick in, but when it does, the effects last for hours.
It’s not for smoking, but it shines in long-lasting, therapeutic use.
With patience and the right method, you can get the most out of what RSO has to offer.
Ready to get started? RickSimpsonOil.com offers syringes, tinctures, gummies, capsules, and more – lab-tested, American-grown, and shipped straight to your door.
How to Use RSO: Frequently Asked Questions
Here are some questions our customers frequently ask us about how to use RSO:
How Should RSO Be Stored?
Store RSO in a cool, dark place like a cabinet or drawer, away from heat and sunlight. Some people refrigerate it to extend shelf life, but that’s optional. Just make sure the cap or plunger is sealed tightly between uses to keep the oil fresh and potent.
What Does RSO High Feel Like?
The RSO high is strong, full-body, and long-lasting. Most people describe it as deeply relaxing or sedating, especially at higher doses. It’s often used to ease pain, stress, or help with sleep, so give yourself time to unwind while it’s working.
How Do You Use RSO Syringe Orally?
Squeeze out about one-third the size of a full grain of rice onto a spoon, cracker, or piece of food, then swallow. Start low – RSO is very potent – and give it plenty of time to work before considering a second dose.
Is RSO Oil Stronger Than Edibles?
Yes – RSO is usually stronger than standard edibles. It’s a full-spectrum cannabis extract with no added ingredients and higher cannabinoid content, so the effects tend to be more intense, longer-lasting, and deeply therapeutic.
