Best RSO Tinctures: 5 Best Products On The Market in 2026

If you’re shopping for the best Rick Simpson Oil (RSO) tincture, you know there’s a plethora of options available. Not only are there dozens of different extracts and cannabinoid blends to choose from, but the availability of products varies widely. Some are available at dispensaries in select states, while others are only available with a medical cannabis card. 

With so much to consider, choosing a product can be difficult. So to help, we’ve put together a complete guide with some of the best RSO tinctures on the market today. 

A Quick Look at the Best RSO Tinctures in 2026

1. RickSimpsonOil.com Original Formula RSO Tincture

If you’re looking for the effects and benefits of Rick Simpson’s original RSO formula in a clean, easy-to-dose format, our Original Formula RSO Tincture is the best option on the market today.

We make our RSO tincture with high-potency, full-spectrum RSO that contains activated THC, secondary cannabinoids, terpenes, flavonoids, and other naturally-occurring compounds from indica cannabis strains. 

Each bottle contains 1000mg of THC – alongside other cannabis compounds – for powerful therapeutic benefits. 

In this way, our tincture gives you the deep, full-body effects of traditional RSO without forcing you to deal with thick, sticky pure RSO oil from a syringe. 

Our RSO tincture can be taken sublingually for fast absorption, or, you can mix it into food or drinks if you prefer more seamless consumption. 

Either way, you’re getting the powerful effects of Rick Simpson’s original RSO formula in a format that’s easier to measure, easier to take, and easier to work into your daily routine.

Pros

• Uses original full-spectrum RSO formula with activated cannabinoids, terpenes, and flavonoids
• Can be used sublingually or mixed into food and drinks
• Available for sale online, delivered directly to your doorstep

Cons

• Likely too strong for low-tolerance users
• Not available in dispensaries

2. Trulieve Momenta RSO Tinctures

Trulieve’s Momenta RSO Tincture is a popular option in Florida’s medical cannabis market. Trulieve takes their signature RSO and dilutes it into a tincture format, making it easier for you to measure and consume compared to a syringe. 

Each bottle contains 600mg of THC, and these tinctures are available in multiple vibrant flavors, including Mint and Mandarin Orange. 

Feedback from customers is mixed, but informative. Some people say they didn’t feel much at first, then felt extremely strong effects after increasing the dose. Others say the taste is pleasant but the effects can feel underwhelming at lower servings. 

Based on this, Trulieve’s RSO tinctures may be a great fit if you’re patient with dosing and willing to take the time to dial in the amount that works with you. 

If you’re in Florida, Georgia, Maryland, or one of the many other states with Trulieve locations, their tinctures are worth consideration. 

Pros

• Easier to dose consistently than syringe RSO
• More approachable taste and format than raw RSO

Cons

• More expensive per mg than some RSO syringes
• High-tolerance users may need more than expected

3. Treeworks RSO Tinctures

Treeworks makes full-spectrum RSO tinctures in functional, effect-specific blends. Their broad tincture lineup includes options like Daily Drops, Dream Drops, Relief Drops, Gentle Drops, and Rocket Drops, each designed around a different use case.

Because Treeworks uses real RSO, you still get the deeper, more complete effects people want from full-spectrum cannabis extract. But instead of choosing a single generic high-THC oil, you can pick a formula based on what you need: daytime use, sleep, relief, or gentler CBD-rich support.

This is where Treeworks stands out. If you’re taking RSO medicinally, you want the strong mental and physical effects, but you probably also want something that suits how and when you’re using RSO. A sleep-focused formula with CBN feels very different from a daytime formula with CBG or THCV, and Treeworks gives you that flexibility. 

If you want RSO effects with more targeted outcomes, Treeworks is a great brand to look for.

Pros

• Uses full-spectrum RSO
• Multiple effect-specific formulas
• Options with THC, CBD, CBG, CBN, and THCV

Cons

• Mostly available in New England markets
• Some formulas are not traditional high-THC RSO

4. RISE RSO Tincture

RISE’s 200mg RSO tincture is popular in Michigan cannabis dispensaries. It’s a full-spectrum RSO tincture formulated with refined hemp seed oil, bringing you this highly beneficial extract in an easy-to-take format.

RISE’s tincture is one of the most approachable options there. At 200mg THC per bottle, it’s much easier to control than a high-potency syringe or a 600mg+ tincture. That makes it a better fit if you want RSO benefits but don’t want to jump straight into a heavy, couch-lock style experience.

This means RISE RSO tinctures are great if you have low to moderate cannabis tolerance and need support for pain, inflammation, relaxation, or general therapeutic use. This tincture will still deliver full-spectrum RSO effects, but its lower potency makes it easier for you to start small and avoid overdoing it.

If you’re new to RSO tinctures, RISE is a good entry point. If you’re a high-tolerance medical user treating cancer or serious discomfort, though, you may want something stronger.

Pros

• Lower-dose 200mg bottle makes it easy to control effects
• Good entry point for lower-tolerance users

Cons

• Not ideal for high-tolerance users
• Less powerful than 600mg+ tinctures or 1g syringes

5. Siskiyou Sungrown RSO MCT Tincture

Siskiyou Sungrown makes several RSO-based tinctures, including THC, CBD, and 1:1 formulas. Their RSO MCT tinctures combine classic RSO with certified organic MCT oil and Oregon mint in a one-once dropper bottle.

This is one of the clearest real RSO tincture options because Siskiyou specifically states that their tinctures are made with classic RSO. That matters because many tinctures are made with generic cannabis oil, distillate, or lighter full-spectrum extracts that don’t deliver you the same level of therapeutic benefit as traditional RSO. 

The MCT oil and mint flavor make the product easier to take, while the graduated dropper gives you more control over your dose. You can use it sublingually for faster uptake or swallow it for a longer-lasting edible-style effect.

If you want true RSO in a clean tincture format, Siskiyou Sungrown is one of the best options out there. The only real drawback is availability, since their tinctures are mostly available in Oregon markets.

Pros

• Real RSO-based tincture
• THC, CBD, and 1:1 options available

Cons

• Mostly tied to Oregon availability
• Mint/MCT flavor may not appeal to everyone

Things to Look for When Shopping for RSO Tinctures

Here’s what you should consider when choosing an RSO tincture:

Potency And Total Cannabinoid Content

Potency is the first thing you’ll want to check when buying an RSO tincture. Start with total THC per bottle, then look at how much THC you get per serving or full dropper.

RSO tinctures can range from about 200mg to 1500mg+ per bottle, so strength varies a lot. Higher-potency tinctures can create stronger, longer-lasting effects, but they’re also easier to overdo if you’re not careful.

Look for clear dosing per dropper, ideally in mg per ml, so you know exactly how much you’re taking. Choose the potency of tincture that best fits your ideal RSO dosage instead of defaulting to the strongest option.

Full-Spectrum vs. Distillate-Based Formulas

The best RSO tinctures use true full-spectrum RSO or FECO, not THC distillate blends. Full-spectrum products contain THC, minor cannabinoids like CBN and CBG, terpenes, flavonoids, and other plant compounds.

These blends create a stronger, longer-lasting encourage effect than cleaner – yet flatter – distillate highs. 

If you’re using RSO for deep body relief, sleep, appetite, or medical-style support, choosing a tincture made with real full-spectrum extract is non-negotiable.

If a tincture doesn’t mention full-spectrum, FECO, or RSO specifically, it’s probably not the real thing. Look for brands that clearly explain the extract type instead of hiding behind vague “cannabis oil” language.

Also, choose a tincture with a cannabinoid blend that supports the specific effects you want. We offer both our Original Formula tincture, made with indica cannabis for sleep support, and our DayTime Formula tincture, made with sativa cannabis strains for increased energy and mental clarity. 

Lab Testing And Transparency

Always verify third-party lab testing before buying an RSO tincture. A quality COA will confirm THC potency, total cannabinoid content, and extract safety.

Look for testing on pesticides, residual solvents, heavy metals, and other contaminants. This is especially important for RSO because traditional RSO uses solvent extraction.

A full cannabinoid breakdown also helps confirm whether the tincture is actually full-spectrum RSO. Brands that clearly show test results are usually more reliable and consistent.

RSO Tinctures vs. RSO Syringes

RSO tinctures and RSO syringes both deliver strong full-spectrum cannabis effects, but tinctures are usually easier to dose, easier to take, and more versatile.

Here’s how the two products stack up:

• Dosing Precision: Tincture droppers are typically metered, so you can measure exact amounts instead of guessing with thick syringe oil. This makes tinctures a better fit if you want a controlled daily routine.
• Onset: When you take a tincture sublingually, you’ll feel the effects in 10-15 minutes. Swallowed RSO from a syringe usually acts more like an edible and may take up to 2 hours to fully kick in.
• Versatility: Tinctures are already blended into a carrier oil, so you can take them under your tongue or add them to food and drinks. Syringes offer higher potency, but pure RSO oil is harder to consume orally due to its thick, sticky consistency. Tinctures are often easier for most people to use day to day.

Get Original-Formula RSO Tinctures Delivered to Your Doorstep

When you want RSO tinctures made with real, original-formula RSO delivered directly to your doorstep, our online store is the place to go. 

We offer two RSO tinctures so you can find something that fits your needs:

• Original Formula RSO Tincture: Made with indica cannabis strains for relaxing, sedative effects. 
• DayTime Formula RSO Tincture: Made with sativa cannabis strains for uplifting, energizing effects. 

Choose the option that best fits the effects you want and the time of day you prefer to consume your RSO. Whichever you pick, you’ll get 1,000mg of real RSO in each bottle for powerful therapeutic benefits. 

Buy RSO Tinctures Online

Looking for more RSO products? Check out our other guides:

• Best RSO Brands
• Best RSO Syringes
• Best RSO Gummies

Best RSO Tinctures: Frequently Asked Questions

Here are some questions we’re frequently asked about RSO tinctures:

What Is The Best Brand Of RSO?

The best RSO brand depends on what you value most. Some brands focus on maximum potency, while others prioritize consistency or cleaner formulations. Look for full-spectrum RSO with verified lab testing and dosing that matches your tolerance. If you want original-formula RSO delivered directly to your doorstep, the best option is RickSimpsonOil.com, the official Rick Simpson Oil website. 

Is RSO Stronger Than Tincture?

RSO is typically stronger than standard THC tinctures because it’s a concentrated, full-spectrum extract rather than a diluted oil. However, RSO tinctures can offer similar effects with more controlled dosing.

Do RSO Tinctures Get You High?

Yes, RSO tinctures can get you high because they contain activated THC along with other cannabinoids. The effects are often heavier and longer-lasting than regular THC tinctures.

How Long Does It Take For RSO Tincture To Kick In?

RSO tinctures usually take 15 to 45 minutes to kick in when taken sublingually and up to 1-2 hours if swallowed. Effects typically last 4-6 hours.